In which stage of Interphase does DNA replication occur?

During the cell cycle, interphase is divided into three stages: G1 (Gap 1), S (Synthesis), and G2 (Gap 2). DNA replication specifically occurs during the S phase. This is a critical period when the cell synthesizes a complete set of DNA, effectively doubling the genetic material in preparation for cell division.

The S phase is characterized by the unwinding of the double helix and the synthesis of new complementary strands through the action of DNA polymerases. The accurate replication of DNA is essential for ensuring that each daughter cell receives an identical set of chromosomes after division.

In contrast, during the G1 phase, the cell focuses on growth and the production of proteins necessary for DNA replication, while in the G2 phase, the cell continues to grow and makes the final preparations for mitosis, such as synthesizing proteins required for chromosome sorting and division. The option labeled "Inhibition" does not correlate to any recognized phase of the cell cycle. Thus, S phase is the only correct answer regarding when DNA replication occurs.