What is chromatin made of?

Chromatin is a substance found within the chromosomes of eukaryotic cells and is composed primarily of DNA and proteins. The main type of proteins in chromatin are histones, which help package the DNA into a compact structure, allowing it to fit within the nucleus of the cell. The combination of DNA and histones forms nucleosomes, which are the fundamental units of chromatin. This structure not only organizes DNA but also plays a crucial role in regulating gene expression and ensuring proper DNA replication and repair.

The other options do not accurately describe the composition of chromatin. While RNA can be present in the cell and is involved in various processes, it is not a component of chromatin. Likewise, DNA, as the genetic material, is indeed essential, but it does not exist in isolation within chromatin; it is associated with proteins. Nucleotides are the building blocks of DNA and RNA, but they do not represent the overall structure of chromatin, and enzymes are not a fundamental part of chromatin itself. Thus, the accurate depiction of chromatin's structure is its composition of DNA and proteins.