Which base pairs with Guanine in DNA?

In DNA, the base that pairs with Guanine is Cytosine. This is due to the specific base pairing rules established by Chargaff's rules and the structure of DNA. Guanine and Cytosine form three hydrogen bonds between them, making this pairing particularly strong compared to other base pairings.

In DNA, the four nitrogenous bases are Adenine, Thymine, Guanine, and Cytosine. Adenine pairs with Thymine, while Guanine is specifically paired with Cytosine. This complementary base pairing is crucial for the double helical structure of DNA and ensures proper replication and transcription processes in cellular activities.

Uracil is not a base found in DNA; it is present in RNA, where it pairs with Adenine instead. Therefore, only Cytosine correctly pairs with Guanine in the context of DNA.